ey (Drosophila virilis)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		FBgn0028754 T237542_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.989 0.989
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.989 0.989
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.989 0.989
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.934 0.934
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.934 0.934
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.934 0.934
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.934 0.934
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.934 0.934
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.934 0.934
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.934 0.934
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.934 0.934
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.934 0.934
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.934 0.934
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.934 0.934
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.934 0.934
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.929 0.929
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.929 0.929
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.929 0.929
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.929 0.929
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.929 0.929
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.929 0.929
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.929 0.929
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.929 0.929
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.929 0.929
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.907 0.907
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.907 0.907
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.907 0.907
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0230074 Paired box 99 223
FBpp0230074 Homeodomain 497 553

Links

Other Homeodomain,Paired box family TFs
Other Drosophila virilis TFs

197 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ey Drosophila melanogaster FBgn0005558 D 0.995
ey Drosophila sechellia FBgn0068720 I 0.995
GE14559 Drosophila yakuba FBgn0232158 I 0.995
GG16399 Drosophila erecta FBgn0108631 I 0.995
GI14081 Drosophila mojavensis FBgn0136835 I 0.989
GK13702 Drosophila willistoni FBgn0215710 I 0.989
ey Drosophila pseudoobscura FBgn0018538 I 0.989
ey Drosophila persimilis FBgn0043659 I 0.989
GF22818 Drosophila ananassae FBgn0099812 I 0.984
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.984
L798_11483 Zootermopsis nevadensis L798_11483 I 0.978
TC008176 Tribolium castaneum TC008176 I 0.973
GB50342 Apis mellifera GB50342 I 0.962
NV15820 Nasonia vitripennis NV15820 I 0.962
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.934
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.934
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.934
Pax6 Mus musculus ENSMUSG00000027168 D 0.934
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.934
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.934
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.934
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.934
PAX6 Microcebus murinus ENSMICG00000004089 I 0.934
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.934
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.934
PAX6 Sus scrofa ENSSSCG00000013320 I 0.934
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.934
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.934
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.934
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.934
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.934
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.934
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.934
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.934
PAX6 Gallus gallus ENSGALG00000012123 I 0.934
PAX6 Procavia capensis ENSPCAG00000005165 I 0.934
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.934
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.934
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.934
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.934
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.934
PAX6 Bos taurus ENSBTAG00000004561 I 0.934
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.934
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.934
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.934
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.934
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.934
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.934
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.934
pax6 Xenopus tropicalis XB-GENE-484088 I 0.934
PAX6 Homo sapiens ENSG00000007372 D 0.934
PAX6 Felis catus ENSFCAG00000007094 I 0.934
PAX6 Sorex araneus ENSSARG00000011424 I 0.931
PHUM097050 Pediculus humanus PHUM097050 I 0.930
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.929
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.929
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.929
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.929
pax6b Danio rerio ENSDARG00000045936 I 0.929
pax6a Danio rerio ENSDARG00000103379 I 0.929
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.923
pax6.L Xenopus laevis XB-GENE-865046 I 0.923
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.923
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.923
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.923
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.923
pax6.S Xenopus laevis XB-GENE-6464331 I 0.923
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.923
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.923
NV17076 Nasonia vitripennis NV17076 I 0.923
L798_00712 Zootermopsis nevadensis L798_00712 I 0.923
GB41504 Apis mellifera GB41504 I 0.923
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.923
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.923
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.923
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.923
pax6b Oryzias latipes ENSORLG00000009913 I 0.923
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.922
PAX6 Echinops telfairi ENSETEG00000002655 I 0.919
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.918
GF21877 Drosophila ananassae FBgn0098877 I 0.918
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.918
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.918
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.912
GJ13300 Drosophila virilis FBgn0200526 I 0.912
GI14042 Drosophila mojavensis FBgn0136796 I 0.912
TC007409 Tribolium castaneum TC007409 I 0.912
GL17563 Drosophila persimilis FBgn0155166 I 0.912
GH23963 Drosophila grimshawi FBgn0131420 I 0.912
GK13683 Drosophila willistoni FBgn0215691 I 0.912
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.912
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.912
GE14563 Drosophila yakuba FBgn0232162 I 0.907
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.907
GG16402 Drosophila erecta FBgn0108634 I 0.907
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.907
PAX6 Equus caballus ENSECAG00000021000 I 0.907
toy Drosophila melanogaster FBgn0019650 D 0.907
GM13021 Drosophila sechellia FBgn0167952 I 0.907
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.901
SMAR013763 Strigamia maritima SMAR013763 I 0.901
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.901
D918_01592 Trichuris suis D918_01592 I 0.901
GD24416 Drosophila simulans FBgn0195753 I 0.901
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.896
LotgiG133720 Lottia gigantea LotgiG133720 I 0.890
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.885
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.885
ADAC001560 Anopheles darlingi ADAC001560 I 0.878
AFUN011570 Anopheles funestus AFUN011570 I 0.877
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.877
AMIN002132 Anopheles minimus AMIN002132 I 0.877
ADIR000973 Anopheles dirus ADIR000973 I 0.877
AATE014626 Anopheles atroparvus AATE014626 I 0.877
ACHR009845 Anopheles christyi ACHR009845 I 0.877
AALB006354 Anopheles albimanus AALB006354 I 0.874
AGAP000067 Anopheles gambiae AGAP000067 I 0.872
AFAF017899 Anopheles farauti AFAF017899 I 0.872
AEPI005798 Anopheles epiroticus AEPI005798 I 0.872
AARA001110 Anopheles arabiensis AARA001110 I 0.872
AMEM002691 Anopheles merus AMEM002691 I 0.872
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.872
AMEC013051 Anopheles melas AMEC013051 I 0.872
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.868
AFUN011575 Anopheles funestus AFUN011575 I 0.868
AGAP000063 Anopheles gambiae AGAP000063 I 0.868
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.868
AARA001115 Anopheles arabiensis AARA001115 I 0.868
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.868
AMIN002127 Anopheles minimus AMIN002127 I 0.868
AMEC021831 Anopheles melas AMEC021831 I 0.868
ASIS012967 Anopheles sinensis ASIS012967 I 0.868
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.868
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.868
ADAC003449 Anopheles darlingi ADAC003449 I 0.866
HelroG80374 Helobdella robusta HelroG80374 I 0.863
csin110224 Clonorchis sinensis csin110224 I 0.862
ISCW021772 Ixodes scapularis ISCW021772 I 0.862
AFAF009619 Anopheles farauti AFAF009619 I 0.860
ACHR008920 Anopheles christyi ACHR008920 I 0.859
AAEL002321 Aedes aegypti AAEL002321 I 0.857
L892_g3713 Steinernema scapterisci L892_g3713 I 0.846
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.846
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.846
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.846
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.846
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.846
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.842
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.841
Smp_160670 Schistosoma mansoni Smp_160670 I 0.841
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.841
CBN04513 Caenorhabditis brenneri CBN04513 I 0.841
T265_09221 Opisthorchis viverrini T265_09221 I 0.841
ASIS012617 Anopheles sinensis ASIS012617 I 0.840
A_05170 Schistosoma haematobium A_05170 I 0.835
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.835
CRE07226 Caenorhabditis remanei CRE07226 I 0.835
ACUA021227 Anopheles culicifacies ACUA021227 I 0.835
ACUA016154 Anopheles culicifacies ACUA016154 I 0.830
AEPI005803 Anopheles epiroticus AEPI005803 I 0.830
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.830
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.830
AALB006643 Anopheles albimanus AALB006643 I 0.830
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.830
MCINX016249 Melitaea cinxia MCINX016249 I 0.830
EFV57892 Trichinella spiralis EFV57892 I 0.830
csin101119 Clonorchis sinensis csin101119 I 0.828
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.824
vab-3 Caenorhabditis elegans WBGene00006870 I 0.824
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.824
ISCW006352 Ixodes scapularis ISCW006352 I 0.824
T265_14971 Opisthorchis viverrini T265_14971 I 0.823
D915_07175 Fasciola hepatica D915_07175 I 0.819
D917_00854 Trichinella nativa D917_00854 I 0.817
Smp_170750 Schistosoma mansoni Smp_170750 I 0.808
ADIR000968 Anopheles dirus ADIR000968 I 0.798
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.797
HelroG173449 Helobdella robusta HelroG173449 I 0.791
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.791
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.786
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.757
MESCA003564 Megaselia scalaris MESCA003564 I 0.753
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.743
fgenesh2_pg.scaffold_23000118 Branchiostoma floridae fgenesh2_pg.scaffold_23000118 I 0.743
TsM_000166900 Taenia solium TsM_000166900 I 0.742
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.736
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.736
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.726
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.725
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.720
GH24002 Drosophila grimshawi FBgn0131459 I 0.711
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.709
Sakowv30011253m.g Saccoglossus kowalevskii Sakowv30011253m.g I 0.707
Aan_R006618 Calypte anna Aan_R006618 I 0.703
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.703
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.703
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.703