ENSP00000257915 (Macaca fascicularis)
Grainyhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF04516 (CP2) IPR007604 ENSP00000257915 T199524_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ENSGALG00000002235
M02030_2.00 		Gallus gallus
AACCGGTTA
TAACCGGTT		 PBM
Weirauch et al.(2014)
pTH8565 		0.913 0.913
UBP1
M04893_2.00 		Homo sapiens
NDCYRGHNNNNDCYRGHN
NDCYRGHNNNNDCYRGHN		 SELEX
Yin et al.(2017)
UBP1_eDBD_HT-SELEX 		0.879 0.879
UBP1
M10614_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LBP1_Q6_01 		0.879 0.879
UBP1
M10615_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LBP1_Q6 		0.879 0.879
UBP1
M04894_2.00 		Homo sapiens
DWCYRGHHNNDDCYRGWH
DWCYRGHHNNDDCYRGWH		 SELEX
Yin et al.(2017)
UBP1_eDBD_Methyl-HT-SELEX 		0.879 0.879
TFCP2
M03074_2.00 		Homo sapiens
DAWCCGGTTY
RAACCGGWTH		 SELEX
Jolma et al.(2013)
TFCP2_1 		0.840 0.840
TFCP2
M03075_2.00 		Homo sapiens
WCCGGWWHDAWCYGGW
WCCRGWTHDWWCCGGW		 SELEX
Jolma et al.(2013)
TFCP2_2 		0.840 0.840
TFCP2
M04889_2.00 		Homo sapiens
DWCYRGWHNNDWCYRGWH
DWCYRGWHNNDWCYRGWH		 SELEX
Yin et al.(2017)
TFCP2_eDBD_HT-SELEX 		0.840 0.840
TFCP2
M04891_2.00 		Homo sapiens
AWCYGGTTHNDACCGGTW
WACCGGTHNDAACCRGWT		 SELEX
Yin et al.(2017)
TFCP2_FL_HT-SELEX 		0.840 0.840
TFCP2
M10610_2.00 		Homo sapiens
CTKGKTHKDGC
GCHMDAMCMAG		 Transfac
Matys et al.(2006)
V$CP2_01 		0.840 0.840
TFCP2
M10611_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CP2_02 		0.840 0.840
TFCP2
M10612_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CP2_Q4 		0.840 0.840
TFCP2
M10613_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CP2_Q6 		0.840 0.840
TFCP2
M04890_2.00 		Homo sapiens
DWCYRGWHNNDWCYRGWH
DWCYRGWHNNDWCYRGWH		 SELEX
Yin et al.(2017)
TFCP2_eDBD_Methyl-HT-SELEX 		0.840 0.840
TFCP2
M04892_2.00 		Homo sapiens
AWCCGGWTNDAWCCGGTT
AACCGGWTHNAACCGGWT		 SELEX
Yin et al.(2017)
TFCP2_FL_Methyl-HT-SELEX 		0.840 0.840
TFCP2L1
M04885_2.00 		Homo sapiens
DCYRGHHNNNDCYRGH
DCYRGHNNNDDCYRGH		 SELEX
Yin et al.(2017)
TFCP2L1_eDBD_HT-SELEX 		0.806 0.806
TFCP2L1
M10609_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LBP9_01 		0.806 0.806
TFCP2L1
M04886_2.00 		Homo sapiens
DCYRGHHNNDDCYRGH
DCYRGHHNNDDCYRGH		 SELEX
Yin et al.(2017)
TFCP2L1_eDBD_Methyl-HT-SELEX 		0.806 0.806
Tcfcp2l1
M08029_2.00 		Mus musculus
CYRGYYYHDDCYRGHYYNNNN
NNNNRRDCYRGHHDRRRCYRG		 ChIP-seq
Chen et al.(2011)
SRP000217_Tcfc2pI1 		0.782 0.782
Tcfcp2l1
M08030_2.00 		Mus musculus
CYRGYYYHDDCYRGHYYNNNN
NNNNRRDCYRGHHDRRRCYRG		 ChIP-seq
Chen et al.(2011)
SRP000217_Tcfcp2I1 		0.782 0.782
Tcfcp2l1
M09127_2.00 		Mus musculus
DDCYRGYTYHNDCYRGHYB
VRDCYRGHNDRARCYRGHH		 Misc
Kulakovskiy et al.(2013)
TF2L1_MOUSE.H11MO.0.C 		0.782 0.782
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000257915 Grainyhead 9 223

Links

Other Grainyhead family TFs
Other Macaca fascicularis TFs

194 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSSTOG00000009123 Ictidomys tridecemlineatus ENSSTOG00000009123 I 1.000
ENSPANG00000019744 Papio anubis ENSPANG00000019744 I 1.000
TFCP2 Callithrix jacchus ENSCJAG00000017599 I 1.000
ENSDNOG00000017309 Dasypus novemcinctus ENSDNOG00000017309 I 0.995
ENSPSIG00000015527 Pelodiscus sinensis ENSPSIG00000015527 I 0.981
Afo_R010616 Aptenodytes forsteri Afo_R010616 I 0.981
Alligator_sinensis_CCG015050.1 Alligator sinensis Alligator_sinensis_CCG015050.1 I 0.981
ENSMPUG00000000711 Mustela putorius furo ENSMPUG00000000711 I 0.975
TFCP2 Pteropus vampyrus ENSPVAG00000014772 I 0.971
ENSTGUG00000015251 Taeniopygia guttata ENSTGUG00000015251 I 0.969
TFCP2 Homo sapiens ENSG00000135457 D 0.968
ENSAPLG00000012157 Anas platyrhynchos ENSAPLG00000012157 I 0.957
TFCP2 Cavia porcellus ENSCPOG00000007923 I 0.952
tfcp2 Xenopus tropicalis XB-GENE-485720 I 0.948
tfcp2.L Xenopus laevis XB-GENE-865546 I 0.938
AAP78771 Xenopus laevis AAP78771 I 0.929
pou6f1 Takifugu rubripes ENSTRUG00000014900 I 0.927
TFCP2 Oryctolagus cuniculus ENSOCUG00000009026 I 0.927
AAI06326 Xenopus laevis AAI06326 I 0.924
TFCP2 Pan troglodytes ENSPTRG00000004949 I 0.922
ENSPPYG00000004522 Pongo abelii ENSPPYG00000004522 I 0.922
ENSCSAG00000005909 Chlorocebus sabaeus ENSCSAG00000005909 I 0.922
TFCP2 Canis familiaris ENSCAFG00000007831 I 0.922
ENSAMEG00000002108 Ailuropoda melanoleuca ENSAMEG00000002108 I 0.922
ENSSHAG00000000901 Sarcophilus harrisii ENSSHAG00000000901 I 0.922
TFCP2 Macaca mulatta ENSMMUG00000000152 I 0.922
ENSNLEG00000017779 Nomascus leucogenys ENSNLEG00000017779 I 0.922
TFCP2 Felis catus ENSFCAG00000030292 I 0.922
TFCP2 Equus caballus ENSECAG00000020650 I 0.922
TFCP2 Otolemur garnettii ENSOGAG00000007969 I 0.922
TFCP2 Vicugna pacos ENSVPAG00000007617 I 0.917
Myotis_brandtii_TFCP2_10023086 Myotis brandtii Myotis_brandtii_TFCP2_10023086 I 0.913
Aan_R009566 Calypte anna Aan_R009566 I 0.913
Tal_R010177 Tyto alba Tal_R010177 I 0.913
ENSOARG00000017390 Ovis aries ENSOARG00000017390 I 0.913
ENSLACG00000012609 Latimeria chalumnae ENSLACG00000012609 I 0.911
Pvit_07455 Pogona vitticeps Pvit_07455 I 0.908
Cmyd_10002729 Chelonia mydas Cmyd_10002729 I 0.908
Tfcp2 Mus musculus ENSMUSG00000009733 I 0.903
Tfcp2 Rattus norvegicus ENSRNOG00000032395 I 0.900
tfcp2 Tetraodon nigroviridis ENSTNIG00000012528 I 0.900
ENSP00000283628-D2 Bos grunniens ENSP00000283628-D2 I 0.896
TFCP2 Bos taurus ENSBTAG00000019312 I 0.896
TFCP2 Loxodonta africana ENSLAFG00000009123 I 0.896
TFCP2 Myotis lucifugus ENSMLUG00000013918 I 0.896
ENSGALG00000002235 Gallus gallus ENSGALG00000002235 D 0.895
TFCP2 Ochotona princeps ENSOPRG00000005747 I 0.891
TFCP2 Anolis carolinensis ENSACAG00000012289 I 0.886
TFCP2 Tursiops truncatus ENSTTRG00000013836 I 0.886
UBP1 Homo sapiens ENSG00000153560 D 0.879
Gfo_R015659 Geospiza fortis Gfo_R015659 I 0.877
ENSLACG00000000718 Latimeria chalumnae ENSLACG00000000718 I 0.875
UBP1 Macaca mulatta ENSMMUG00000016917 I 0.874
ENSP00000283629 Macaca fascicularis ENSP00000283629 I 0.874
ENSCSAG00000009395 Chlorocebus sabaeus ENSCSAG00000009395 I 0.874
ENSNLEG00000004651 Nomascus leucogenys ENSNLEG00000004651 I 0.874
UBP1 Myotis lucifugus ENSMLUG00000010827 I 0.874
UBP1 Callithrix jacchus ENSCJAG00000012030 I 0.874
UBP1 Pteropus vampyrus ENSPVAG00000004158 I 0.874
UBP1 Pan troglodytes ENSPTRG00000014733 I 0.874
ENSPPYG00000014030 Pongo abelii ENSPPYG00000014030 I 0.874
UBP1 Cavia porcellus ENSCPOG00000009270 I 0.874
UBP1 Oryctolagus cuniculus ENSOCUG00000011063 I 0.874
ENSPMAG00000007229 Petromyzon marinus ENSPMAG00000007229 I 0.871
ENSPANG00000003702 Papio anubis ENSPANG00000003702 I 0.869
UBP1 Bos taurus ENSBTAG00000003968 I 0.869
tfcp2 Danio rerio ENSDARG00000060306 I 0.869
ENSMPUG00000013008 Mustela putorius furo ENSMPUG00000013008 I 0.865
UBP1 Canis familiaris ENSCAFG00000004598 I 0.865
ENSAMEG00000002341 Ailuropoda melanoleuca ENSAMEG00000002341 I 0.865
ENSAMXG00000016608 Astyanax mexicanus ENSAMXG00000016608 I 0.864
tfcp2 Oryzias latipes ENSORLG00000015644 I 0.864
tfcp2 Gasterosteus aculeatus ENSGACG00000010929 I 0.864
UBP1 Ochotona princeps ENSOPRG00000012913 I 0.861
UBP1 Otolemur garnettii ENSOGAG00000000962 I 0.861
Ubp1 Rattus norvegicus ENSRNOG00000009729 I 0.859
Pvit_12019 Pogona vitticeps Pvit_12019 I 0.859
Ogr17000 Ophisaurus gracilis Ogr17000 I 0.859
ENSOARG00000015881 Ovis aries ENSOARG00000015881 I 0.856
UBP1 Ornithorhynchus anatinus ENSOANG00000008309 I 0.854
ENSAPLG00000001472 Anas platyrhynchos ENSAPLG00000001472 I 0.854
Gfo_R001955 Geospiza fortis Gfo_R001955 I 0.850
Afo_R010081 Aptenodytes forsteri Afo_R010081 I 0.850
UBP1 Anolis carolinensis ENSACAG00000013565 I 0.850
ENSFALG00000004962 Ficedula albicollis ENSFALG00000004962 I 0.850
Aan_R001501 Calypte anna Aan_R001501 I 0.850
ENSLOCG00000002718 Lepisosteus oculatus ENSLOCG00000002718 I 0.850
Brh_R008147 Buceros rhinoceros Brh_R008147 I 0.850
ENSLOCG00000004816 Lepisosteus oculatus ENSLOCG00000004816 I 0.850
Tal_R012945 Tyto alba Tal_R012945 I 0.850
ENSONIG00000016680 Oreochromis niloticus ENSONIG00000016680 I 0.848
ENSXMAG00000005202 Xiphophorus maculatus ENSXMAG00000005202 I 0.845
ENSGALG00000011980 Gallus gallus ENSGALG00000011980 I 0.842
Ubp1 Mus musculus ENSMUSG00000009741 I 0.842
ENSGMOG00000007483 Gadus morhua ENSGMOG00000007483 I 0.835
Ogr01415 Ophisaurus gracilis Ogr01415 I 0.833
ENSDNOG00000019550 Dasypus novemcinctus ENSDNOG00000019550 I 0.831
ENSONIG00000002320 Oreochromis niloticus ENSONIG00000002320 I 0.830
ENSGMOG00000010354 Gadus morhua ENSGMOG00000010354 I 0.825
Myotis_brandtii_UBP1_10023937 Myotis brandtii Myotis_brandtii_UBP1_10023937 I 0.825
ENSPFOG00000011621 Poecilia formosa ENSPFOG00000011621 I 0.822
UBP1 Equus caballus ENSECAG00000018555 I 0.820
ubp1 Takifugu rubripes ENSTRUG00000013570 I 0.820
UBP1 Sus scrofa ENSSSCG00000011235 I 0.820
UBP1 Felis catus ENSFCAG00000006123 I 0.820
ubp1 Gasterosteus aculeatus ENSGACG00000005520 I 0.820
ENSLAFG00000030783 Loxodonta africana ENSLAFG00000030783 I 0.817
ENSSHAG00000002389 Sarcophilus harrisii ENSSHAG00000002389 I 0.816
TFCP2L1 Taeniopygia guttata ENSTGUG00000004573 I 0.816
ENSP00000283628-D1 Bos grunniens ENSP00000283628-D1 I 0.816
Ubp1 Dipodomys ordii ENSDORG00000010133 I 0.816
UBP1 Sorex araneus ENSSARG00000008670 I 0.816
ENSMODG00000002605 Monodelphis domestica ENSMODG00000002605 I 0.815
ENSPMAG00000006794 Petromyzon marinus ENSPMAG00000006794 I 0.813
UBP1 Procavia capensis ENSPCAG00000008237 I 0.812
Afo_R006827 Aptenodytes forsteri Afo_R006827 I 0.811
Tal_R011103 Tyto alba Tal_R011103 I 0.811
Aan_R003641 Calypte anna Aan_R003641 I 0.811
Brh_R004848 Buceros rhinoceros Brh_R004848 I 0.811
Gfo_R001211 Geospiza fortis Gfo_R001211 I 0.811
UBP1 Tursiops truncatus ENSTTRG00000016791 I 0.808
TFCP2L1 Meleagris gallopavo ENSMGAG00000011889 I 0.806
TFCP2L1 Gallus gallus ENSGALG00000011635 I 0.806
ENSSHAG00000013877 Sarcophilus harrisii ENSSHAG00000013877 I 0.806
TFCP2L1 Cavia porcellus ENSCPOG00000011523 I 0.806
ENSTSYG00000013882 Tarsius syrichta ENSTSYG00000013882 I 0.806
TFCP2L1 Microcebus murinus ENSMICG00000007161 I 0.806
ENSDNOG00000018905 Dasypus novemcinctus ENSDNOG00000018905 I 0.806
TFCP2L1 Gorilla gorilla ENSGGOG00000001680 I 0.806
TFCP2L1 Pan troglodytes ENSPTRG00000012415 I 0.806
Cmyd_10009085 Chelonia mydas Cmyd_10009085 I 0.806
TFCP2L1 Monodelphis domestica ENSMODG00000000229 I 0.806
TFCP2L1 Oryctolagus cuniculus ENSOCUG00000006877 I 0.806
TFCP2L1 Anolis carolinensis ENSACAG00000004268 I 0.806
TFCP2L1 Ornithorhynchus anatinus ENSOANG00000007591 I 0.806
ENSPMAG00000003474 Petromyzon marinus ENSPMAG00000003474 I 0.806
ENSNLEG00000000988 Nomascus leucogenys ENSNLEG00000000988 I 0.806
tfcp2l1.S Xenopus laevis XB-GENE-6255174 I 0.802
ENSPSIG00000008408 Pelodiscus sinensis ENSPSIG00000008408 I 0.802
TFCP2L1 Callithrix jacchus ENSCJAG00000013356 I 0.801
ENSAMEG00000005284 Ailuropoda melanoleuca ENSAMEG00000005284 I 0.801
tfcp2l1.L Xenopus laevis XB-GENE-997202 I 0.801
TFCP2L1 Equus caballus ENSECAG00000024837 I 0.801
Pvit_06471 Pogona vitticeps Pvit_06471 I 0.801
TFCP2L1 Canis familiaris ENSCAFG00000004788 I 0.801
ENSFALG00000013230 Ficedula albicollis ENSFALG00000013230 I 0.799
Tfcp2l1 Rattus norvegicus ENSRNOG00000002414 I 0.797
ENSSTOG00000013080 Ictidomys tridecemlineatus ENSSTOG00000013080 I 0.796
ENSMPUG00000001036 Mustela putorius furo ENSMPUG00000001036 I 0.796
TFCP2L1 Sus scrofa ENSSSCG00000015732 I 0.796
ENSOARG00000013124 Ovis aries ENSOARG00000013124 I 0.796
ENSLACG00000017694 Latimeria chalumnae ENSLACG00000017694 I 0.795
TFCP2L1 Otolemur garnettii ENSOGAG00000012031 I 0.794
ENSPANG00000016702 Papio anubis ENSPANG00000016702 I 0.794
TFCP2L1 Homo sapiens ENSG00000115112 D 0.794
ENSPPYG00000012777 Pongo abelii ENSPPYG00000012777 I 0.794
ENSCSAG00000016679 Chlorocebus sabaeus ENSCSAG00000016679 I 0.794
UBP1 Echinops telfairi ENSETEG00000016510 I 0.793
TFCP2L1 Bos taurus ENSBTAG00000007765 I 0.791
TFCP2L1 Felis catus ENSFCAG00000012143 I 0.791
ENSSTOG00000012083 Ictidomys tridecemlineatus ENSSTOG00000012083 I 0.791
ENSAPLG00000015648 Anas platyrhynchos ENSAPLG00000015648 I 0.789
ENSP00000263707-D1 Bos grunniens ENSP00000263707-D1 I 0.786
Myotis_brandtii_TFCP2L1_10019079 Myotis brandtii Myotis_brandtii_TFCP2L1_10019079 I 0.786
ENSXMAG00000003023 Xiphophorus maculatus ENSXMAG00000003023 I 0.786
Alligator_sinensis_CCG001515.1 Alligator sinensis Alligator_sinensis_CCG001515.1 I 0.784
ENSPFOG00000008378 Poecilia formosa ENSPFOG00000008378 I 0.782
TFCP2L1 Erinaceus europaeus ENSEEUG00000011003 I 0.782
ENSSHAG00000002647 Sarcophilus harrisii ENSSHAG00000002647 I 0.782
UBP1 Meleagris gallopavo ENSMGAG00000011814 I 0.780
TFCP2L1 Loxodonta africana ENSLAFG00000006873 I 0.780
Tcfcp2l1 Mus musculus ENSMUSG00000026380 D 0.778
ubp1 Tetraodon nigroviridis ENSTNIG00000016974 I 0.777
ubp1 Oryzias latipes ENSORLG00000011706 I 0.772
ENSLOCG00000002070 Lepisosteus oculatus ENSLOCG00000002070 I 0.767
ENSFALG00000004724 Ficedula albicollis ENSFALG00000004724 I 0.767
ENSPSIG00000003763 Pelodiscus sinensis ENSPSIG00000003763 I 0.762
TFCP2 Echinops telfairi ENSETEG00000010787 I 0.757
ENSSHAG00000005805 Sarcophilus harrisii ENSSHAG00000005805 I 0.757
TFCP2 Procavia capensis ENSPCAG00000014181 I 0.754
ENSMODG00000014457 Monodelphis domestica ENSMODG00000014457 I 0.752
TFCP2L1 Macaca mulatta ENSMMUG00000008829 I 0.752
Alligator_sinensis_CCG001336.1 Alligator sinensis Alligator_sinensis_CCG001336.1 I 0.750
tfcp2l1 Danio rerio ENSDARG00000029497 N 0.743
ubp1 Danio rerio ENSDARG00000018000 I 0.742
ENSACAG00000017482 Anolis carolinensis ENSACAG00000017482 I 0.728
UBP1 Taeniopygia guttata ENSTGUG00000001752 I 0.728
Ogr16171 Ophisaurus gracilis Ogr16171 I 0.723
ENSPFOG00000001485 Poecilia formosa ENSPFOG00000001485 N 0.722
ENSPFOG00000014602 Poecilia formosa ENSPFOG00000014602 N 0.718
ENSECAG00000023454 Equus caballus ENSECAG00000023454 I 0.717
ENSSHAG00000001157 Sarcophilus harrisii ENSSHAG00000001157 I 0.717
Pvit_07635 Pogona vitticeps Pvit_07635 I 0.714
Alligator_sinensis_CCG020804.1 Alligator sinensis Alligator_sinensis_CCG020804.1 N 0.709