cux1a (Danio rerio)
CUT,Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02376 (CUT)
PF00046 (Homeobox) 		IPR003350
IPR001356 		ENSDARG00000078459 T167017_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in brain. Orthologous to human CUX1 (cut like homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CUX1
M02946_2.00 		Homo sapiens
ATCRATHNNNDATCRAT
ATYGATHNNNDATYGAT		 SELEX
Jolma et al.(2013)
CUX1_1 		0.937 0.937
CUX1
M02947_2.00 		Homo sapiens
ATCRATHNNNNDATCRAT
ATYGATHNNNNDATYGAT		 SELEX
Jolma et al.(2013)
CUX1_2 		0.937 0.937
CUX1
M02948_2.00 		Homo sapiens
TDATCRATNN
NNATYGATHA		 SELEX
Jolma et al.(2013)
CUX1_3 		0.937 0.937
CUX1
M04679_2.00 		Homo sapiens
NDATCRATNN
NNATYGATHN		 SELEX
Yin et al.(2017)
CUX1_eDBD_HT-SELEX 		0.937 0.937
CUX1
M09023_2.00 		Homo sapiens
RBRVNDATYGRTBN
NVAYCRATHNBYVY		 Misc
Kulakovskiy et al.(2013)
CUX1_HUMAN.H11MO.0.C 		0.937 0.937
Cux1
M09024_2.00 		Mus musculus
RBRVNDATYGRTBN
NVAYCRATHNBYVY		 Misc
Kulakovskiy et al.(2013)
CUX1_MOUSE.H11MO.0.C 		0.937 0.937
CUX1
M10422_2.00 		Homo sapiens
CCAATAATCRAT
ATYGATTATTGG		 Transfac
Matys et al.(2006)
V$CDP_01 		0.937 0.937
CUX1
M10423_2.00 		Homo sapiens
DWDATCGATYADHDH
DHDHTRATCGATHWH		 Transfac
Matys et al.(2006)
V$CDP_02 		0.937 0.937
CUX1
M10424_2.00 		Homo sapiens
SCVATCRATN
NATYGATBGS		 Transfac
Matys et al.(2006)
V$CDPCR1_01 		0.937 0.937
CUX1
M10425_2.00 		Homo sapiens
CVATABNTATYKGTG
CACMRATANVTATBG		 Transfac
Matys et al.(2006)
V$CDPCR3_01 		0.937 0.937
CUX1
M10426_2.00 		Homo sapiens
SVSATCRATB
VATYGATSBS		 Transfac
Matys et al.(2006)
V$CDPCR3HD_01 		0.937 0.937
CUX1
M10427_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDP_Q6_01 		0.937 0.937
CUX1
M10416_2.00 		Canis familiaris
DHDATYGATYADYDW
WHRHTRATCRATHDH		 Transfac
Matys et al.(2006)
V$CLOX_01 		0.937 0.937
CUX1
M04680_2.00 		Homo sapiens
NBATTGATHR
YDATCAATVN		 SELEX
Yin et al.(2017)
CUX1_eDBD_Methyl-HT-SELEX 		0.937 0.937
CUX2
M02940_2.00 		Homo sapiens
ATCRATAHNNDWATCGAT
ATCGATWHNNDTATYGAT		 SELEX
Jolma et al.(2013)
CUX2_1 		0.868 0.868
CUX2
M02941_2.00 		Homo sapiens
DDATYGATYA
TRATCRATHH		 SELEX
Jolma et al.(2013)
CUX2_2 		0.868 0.868
CUX2
M04665_2.00 		Homo sapiens
NTRATCGATYRN
NYRATCGATYAN		 SELEX
Yin et al.(2017)
CUX2_eDBD_HT-SELEX 		0.868 0.868
CUX2
M04666_2.00 		Homo sapiens
BYRATCGATYRB
VYRATCGATYRV		 SELEX
Yin et al.(2017)
CUX2_eDBD_Methyl-HT-SELEX 		0.868 0.868
Cux2
M09025_2.00 		Mus musculus
NBBATTGATYD
HRATCAATVVN		 Misc
Kulakovskiy et al.(2013)
CUX2_MOUSE.H11MO.0.C 		0.864 0.864
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000075613 CUT 580 657
ENSDARP00000075613 CUT 1005 1080
ENSDARP00000075613 CUT 1159 1237
ENSDARP00000075613 Homeodomain 1297 1353
ENSDARP00000119597 CUT 74 152

Links

Other CUT,Homeodomain family TFs
Other Danio rerio TFs

108 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSLOCG00000001531 Lepisosteus oculatus ENSLOCG00000001531 I 0.958
CUX1 Erinaceus europaeus ENSEEUG00000005128 I 0.948
ENSLACG00000017710 Latimeria chalumnae ENSLACG00000017710 I 0.944
ENSSHAG00000007801 Sarcophilus harrisii ENSSHAG00000007801 I 0.941
CUX1 Monodelphis domestica ENSMODG00000013581 I 0.941
Ogr05066 Ophisaurus gracilis Ogr05066 I 0.941
ENSGALG00000001807 Gallus gallus ENSGALG00000001807 I 0.937
CUX1 Taeniopygia guttata ENSTGUG00000004386 I 0.937
Afo_R009437 Aptenodytes forsteri Afo_R009437 I 0.937
ENSFALG00000009409 Ficedula albicollis ENSFALG00000009409 I 0.937
Alligator_sinensis_CCG004936.1 Alligator sinensis Alligator_sinensis_CCG004936.1 I 0.937
Aan_R003487 Calypte anna Aan_R003487 I 0.937
Cux1 Rattus norvegicus ENSRNOG00000001424 I 0.937
CUX1 Myotis lucifugus ENSMLUG00000007264 I 0.937
CUX1 Macaca mulatta ENSMMUG00000021461 I 0.937
ENSPANG00000016879 Papio anubis ENSPANG00000016879 I 0.937
CUX1 Pan troglodytes ENSPTRG00000019531 I 0.937
ENSNLEG00000008310 Nomascus leucogenys ENSNLEG00000008310 I 0.937
Cux1 Mus musculus ENSMUSG00000029705 D 0.937
CUX1 Homo sapiens ENSG00000257923 D 0.937
ENSP00000353401-D1 Bos grunniens ENSP00000353401-D1 I 0.937
CUX1 Canis familiaris ENSCAFG00000013749 D 0.937
ENSAPLG00000002588 Anas platyrhynchos ENSAPLG00000002588 I 0.937
ENSP00000353401 Macaca fascicularis ENSP00000353401 I 0.937
Gfo_R011360 Geospiza fortis Gfo_R011360 I 0.937
ENSCSAG00000018062 Chlorocebus sabaeus ENSCSAG00000018062 I 0.937
ENSAMXG00000008817 Astyanax mexicanus ENSAMXG00000008817 I 0.937
CUX1 Bos taurus ENSBTAG00000010659 I 0.937
Pvit_01819 Pogona vitticeps Pvit_01819 I 0.937
ENSPSIG00000008210 Pelodiscus sinensis ENSPSIG00000008210 I 0.934
CUX1 Callithrix jacchus ENSCJAG00000016076 I 0.934
Cmyd_10006308 Chelonia mydas Cmyd_10006308 I 0.934
XP_002942311 Xenopus tropicalis XP_002942311 I 0.934
CUX1 Anolis carolinensis ENSACAG00000015088 I 0.930
ENSSTOG00000010390 Ictidomys tridecemlineatus ENSSTOG00000010390 I 0.923
Tal_R013483 Tyto alba Tal_R013483 I 0.920
ENSAMEG00000015392 Ailuropoda melanoleuca ENSAMEG00000015392 I 0.920
CUX1 Loxodonta africana ENSLAFG00000002555 I 0.920
CUX1 Tursiops truncatus ENSTTRG00000014625 I 0.920
CUX1 Felis catus ENSFCAG00000008074 I 0.920
ENSOARG00000014629 Ovis aries ENSOARG00000014629 I 0.920
CUX1 Ochotona princeps ENSOPRG00000000165 I 0.916
Myotis_brandtii_CUX1_10015212 Myotis brandtii Myotis_brandtii_CUX1_10015212 I 0.916
CUX1 Meleagris gallopavo ENSMGAG00000003398 I 0.913
ENSOGAG00000009038 Otolemur garnettii ENSOGAG00000009038 I 0.902
CUX2 Oryctolagus cuniculus ENSOCUG00000021923 I 0.875
CUX2 Dasypus novemcinctus ENSDNOG00000039959 I 0.875
ENSFALG00000009019 Ficedula albicollis ENSFALG00000009019 I 0.875
CUX2 Ochotona princeps ENSOPRG00000006461 I 0.871
CUX2 Pteropus vampyrus ENSPVAG00000013176 I 0.871
ENSSTOG00000002242 Ictidomys tridecemlineatus ENSSTOG00000002242 I 0.871
ENSOARG00000017879 Ovis aries ENSOARG00000017879 I 0.871
CUX2 Canis familiaris ENSCAFG00000008575 I 0.871
ENSAMEG00000013799 Ailuropoda melanoleuca ENSAMEG00000013799 I 0.871
CUX2 Felis catus ENSFCAG00000003176 I 0.871
CUX2 Monodelphis domestica ENSMODG00000012254 I 0.871
CUX2 Bos taurus ENSBTAG00000008571 I 0.868
CUX2 Sus scrofa ENSSSCG00000009831 I 0.868
ENSLACG00000014413 Latimeria chalumnae ENSLACG00000014413 I 0.868
ENSP00000261726-D1 Bos grunniens ENSP00000261726-D1 I 0.868
CUX2 Ornithorhynchus anatinus ENSOANG00000004793 I 0.868
CUX2 Callithrix jacchus ENSCJAG00000011694 I 0.868
CUX2 Homo sapiens ENSG00000111249 D 0.868
Alligator_sinensis_CCG016555.1 Alligator sinensis Alligator_sinensis_CCG016555.1 I 0.868
ENSP00000261726 Macaca fascicularis ENSP00000261726 I 0.868
CUX2 Cavia porcellus ENSCPOG00000020483 I 0.868
CUX2 Tursiops truncatus ENSTTRG00000000945 I 0.868
CUX2 Loxodonta africana ENSLAFG00000001145 I 0.868
ENSSHAG00000009458 Sarcophilus harrisii ENSSHAG00000009458 I 0.868
CUX2 Anolis carolinensis ENSACAG00000002281 I 0.868
ENSNLEG00000000470 Nomascus leucogenys ENSNLEG00000000470 I 0.868
CUX2 Myotis lucifugus ENSMLUG00000003239 I 0.868
ENSLOCG00000007417 Lepisosteus oculatus ENSLOCG00000007417 I 0.868
CUX2 Otolemur garnettii ENSOGAG00000029919 I 0.868
ENSMPUG00000002207 Mustela putorius furo ENSMPUG00000002207 I 0.868
ENSXMAG00000004131 Xiphophorus maculatus ENSXMAG00000004131 I 0.864
Cux2 Mus musculus ENSMUSG00000042589 D 0.864
ENSPFOG00000005210 Poecilia formosa ENSPFOG00000005210 I 0.864
CUX2 Meleagris gallopavo ENSMGAG00000005225 I 0.864
ENSAMXG00000006105 Astyanax mexicanus ENSAMXG00000006105 I 0.864
Myotis_brandtii_CUX2_10011523 Myotis brandtii Myotis_brandtii_CUX2_10011523 I 0.864
Cmyd_10015658 Chelonia mydas Cmyd_10015658 I 0.864
CUX2 Gallus gallus ENSGALG00000004598 I 0.864
cux2 Xenopus tropicalis XB-GENE-487236 I 0.861
Pvit_05599 Pogona vitticeps Pvit_05599 I 0.861
cux2b Danio rerio ENSDARG00000086345 I 0.857
Aan_R010335 Calypte anna Aan_R010335 I 0.857
Gfo_R003142 Geospiza fortis Gfo_R003142 I 0.857
ENSGMOG00000017485 Gadus morhua ENSGMOG00000017485 I 0.857
Cux2 Rattus norvegicus ENSRNOG00000001259 I 0.857
ENSONIG00000015972 Oreochromis niloticus ENSONIG00000015972 I 0.854
cux2b Oryzias latipes ENSORLG00000015973 I 0.854
cux2b Gasterosteus aculeatus ENSGACG00000013522 I 0.854
cux2b Tetraodon nigroviridis ENSTNIG00000011453 I 0.850
cux2b Takifugu rubripes ENSTRUG00000015853 I 0.850
Ogr05872 Ophisaurus gracilis Ogr05872 I 0.847
ENSAPLG00000004382 Anas platyrhynchos ENSAPLG00000004382 I 0.833
CUX1 Microcebus murinus ENSMICG00000010274 I 0.794
ENSGMOG00000008990 Gadus morhua ENSGMOG00000008990 I 0.794
ENSGACG00000009915 Gasterosteus aculeatus ENSGACG00000009915 I 0.770
ENSTNIG00000007722 Tetraodon nigroviridis ENSTNIG00000007722 I 0.770
ENSXMAG00000018520 Xiphophorus maculatus ENSXMAG00000018520 I 0.767
CUX2 Taeniopygia guttata ENSTGUG00000006470 I 0.763
ENSONIG00000003797 Oreochromis niloticus ENSONIG00000003797 I 0.763
CUX1 Pteropus vampyrus ENSPVAG00000017756 I 0.756
CUX1 Takifugu rubripes ENSTRUG00000008546 I 0.753
CUX2 Pan troglodytes ENSPTRG00000005455 I 0.742
CapteG49316 Capitella teleta CapteG49316 N 0.714