nhr-109 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003699 T306221_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-86
M02415_2.00 		Caenorhabditis elegans
KTGTAGTC
GACTACAM		 PBM
Weirauch et al.(2014)
pTH8598 		0.968 0.757
nhr-70
M00695_2.00 		Caenorhabditis elegans
NYTGTAGYYD
HRRCTACARN		 PBM
Narasimhan et al.(2015)
pTH9174 		0.859 0.657
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
T12C9.5a Nuclear receptor 1 17
T12C9.5b Nuclear receptor 8 31
T12C9.5c Nuclear receptor 11 80

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

57 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG12152 Caenorhabditis briggsae CBG12152 I 0.975
CRE18529 Caenorhabditis remanei CRE18529 I 0.975
nhr-273 Caenorhabditis elegans WBGene00020460 I 0.971
nhr-86 Caenorhabditis elegans WBGene00003676 D 0.968
nhr-16 Caenorhabditis elegans WBGene00003615 I 0.950
CBN24070 Caenorhabditis brenneri CBN24070 I 0.950
CRE17354 Caenorhabditis remanei CRE17354 I 0.949
nhr-28 Caenorhabditis elegans WBGene00003624 I 0.946
CBN03769 Caenorhabditis brenneri CBN03769 I 0.944
CBN04619 Caenorhabditis brenneri CBN04619 I 0.944
CRE27659 Caenorhabditis remanei CRE27659 I 0.941
CJA10576 Caenorhabditis japonica CJA10576 I 0.939
CBG03687 Caenorhabditis briggsae CBG03687 I 0.938
CBG16375 Caenorhabditis briggsae CBG16375 I 0.938
CRE17310 Caenorhabditis remanei CRE17310 I 0.931
CJA07390 Caenorhabditis japonica CJA07390 I 0.931
CJA04414 Caenorhabditis japonica CJA04414 I 0.931
SMUV_0000801801 Syphacia muris SMUV_0000801801 I 0.923
CRE17355 Caenorhabditis remanei CRE17355 I 0.917
SMUV_0000886001 Syphacia muris SMUV_0000886001 I 0.915
CBN03440 Caenorhabditis brenneri CBN03440 I 0.915
L892_g8140 Steinernema scapterisci L892_g8140 I 0.913
L596_g27786 Steinernema carpocapsae L596_g27786 I 0.898
L893_g4569 Steinernema glaseri L893_g4569 I 0.892
L892_g8145 Steinernema scapterisci L892_g8145 I 0.892
scaffold1235-EXSNAP2012.2 Pristionchus exspectatus scaffold1235-EXSNAP2012.2 I 0.892
L898_g28806 Steinernema monticolum L898_g28806 I 0.889
L892_g8144 Steinernema scapterisci L892_g8144 I 0.888
L893_g9517 Steinernema glaseri L893_g9517 I 0.886
nhr-12 Caenorhabditis elegans WBGene00003611 I 0.879
CRE07801 Caenorhabditis remanei CRE07801 I 0.878
CBN16902 Caenorhabditis brenneri CBN16902 I 0.878
L898_g10723 Steinernema monticolum L898_g10723 I 0.877
L889_g987 Steinernema feltiae L889_g987 I 0.874
L889_g9698 Steinernema feltiae L889_g9698 I 0.874
L893_g2090 Steinernema glaseri L893_g2090 I 0.867
PPA29361 Pristionchus pacificus PPA29361 I 0.865
CRE27174 Caenorhabditis remanei CRE27174 I 0.861
EVEC_0001266201 Enterobius vermicularis EVEC_0001266201 I 0.860
nhr-70 Caenorhabditis elegans WBGene00003660 D 0.859
L892_g10708 Steinernema scapterisci L892_g10708 I 0.843
L596_g9106 Steinernema carpocapsae L596_g9106 I 0.842
CBG20699 Caenorhabditis briggsae CBG20699 I 0.840
NECAME_01500 Necator americanus NECAME_01500 I 0.837
scaffold183-EXSNAP2012.18 Pristionchus exspectatus scaffold183-EXSNAP2012.18 I 0.835
PPA08785 Pristionchus pacificus PPA08785 I 0.835
PPA10478 Pristionchus pacificus PPA10478 I 0.834
scaffold260-EXSNAP2012.15 Pristionchus exspectatus scaffold260-EXSNAP2012.15 I 0.834
CBG03688 Caenorhabditis briggsae CBG03688 I 0.823
L898_g18539 Steinernema monticolum L898_g18539 I 0.804
SMUV_0000909301 Syphacia muris SMUV_0000909301 I 0.793
EVEC_0001095701 Enterobius vermicularis EVEC_0001095701 I 0.782
L889_g10781 Steinernema feltiae L889_g10781 I 0.776
CRE09011 Caenorhabditis remanei CRE09011 I 0.760
L889_g17146 Steinernema feltiae L889_g17146 I 0.760
nhr-53 Caenorhabditis elegans WBGene00003643 I 0.757