nhr-28 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003624 T306149_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in body wall; head; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-86
M02415_2.00 		Caenorhabditis elegans
KTGTAGTC
GACTACAM		 PBM
Weirauch et al.(2014)
pTH8598 		0.915 0.671
nhr-70
M00695_2.00 		Caenorhabditis elegans
NYTGTAGYYD
HRRCTACARN		 PBM
Narasimhan et al.(2015)
pTH9174 		0.891 0.729
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
C11G6.4a Nuclear receptor 6 75

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

59 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG16375 Caenorhabditis briggsae CBG16375 I 0.985
CJA10576 Caenorhabditis japonica CJA10576 I 0.981
CRE27659 Caenorhabditis remanei CRE27659 I 0.979
CBN04619 Caenorhabditis brenneri CBN04619 I 0.972
nhr-109 Caenorhabditis elegans WBGene00003699 I 0.946
CRE18529 Caenorhabditis remanei CRE18529 I 0.945
CBG12152 Caenorhabditis briggsae CBG12152 I 0.945
CJA04414 Caenorhabditis japonica CJA04414 I 0.932
CJA07390 Caenorhabditis japonica CJA07390 I 0.932
SMUV_0000801801 Syphacia muris SMUV_0000801801 I 0.932
nhr-273 Caenorhabditis elegans WBGene00020460 I 0.929
SMUV_0000886001 Syphacia muris SMUV_0000886001 I 0.921
CBN16902 Caenorhabditis brenneri CBN16902 I 0.920
nhr-86 Caenorhabditis elegans WBGene00003676 D 0.915
CBN03769 Caenorhabditis brenneri CBN03769 I 0.914
CRE27174 Caenorhabditis remanei CRE27174 I 0.907
CRE07801 Caenorhabditis remanei CRE07801 I 0.907
nhr-12 Caenorhabditis elegans WBGene00003611 I 0.906
CBN24070 Caenorhabditis brenneri CBN24070 I 0.899
nhr-70 Caenorhabditis elegans WBGene00003660 D 0.891
CBG20699 Caenorhabditis briggsae CBG20699 I 0.887
L892_g8145 Steinernema scapterisci L892_g8145 I 0.886
L893_g9517 Steinernema glaseri L893_g9517 I 0.886
L893_g4569 Steinernema glaseri L893_g4569 I 0.886
L898_g28806 Steinernema monticolum L898_g28806 I 0.882
L596_g27786 Steinernema carpocapsae L596_g27786 I 0.881
L892_g8144 Steinernema scapterisci L892_g8144 I 0.879
L892_g8140 Steinernema scapterisci L892_g8140 I 0.871
L893_g2090 Steinernema glaseri L893_g2090 I 0.866
CRE17354 Caenorhabditis remanei CRE17354 I 0.866
scaffold183-EXSNAP2012.18 Pristionchus exspectatus scaffold183-EXSNAP2012.18 I 0.866
PPA08785 Pristionchus pacificus PPA08785 I 0.866
scaffold260-EXSNAP2012.15 Pristionchus exspectatus scaffold260-EXSNAP2012.15 I 0.865
PPA10478 Pristionchus pacificus PPA10478 I 0.865
L889_g987 Steinernema feltiae L889_g987 I 0.864
L889_g9698 Steinernema feltiae L889_g9698 I 0.864
EVEC_0001266201 Enterobius vermicularis EVEC_0001266201 I 0.861
CBG03687 Caenorhabditis briggsae CBG03687 I 0.860
L892_g10708 Steinernema scapterisci L892_g10708 I 0.848
L596_g9106 Steinernema carpocapsae L596_g9106 I 0.848
L889_g10781 Steinernema feltiae L889_g10781 I 0.846
L898_g10723 Steinernema monticolum L898_g10723 I 0.844
scaffold1235-EXSNAP2012.2 Pristionchus exspectatus scaffold1235-EXSNAP2012.2 I 0.843
nhr-16 Caenorhabditis elegans WBGene00003615 I 0.843
CRE17310 Caenorhabditis remanei CRE17310 I 0.837
nhr-53 Caenorhabditis elegans WBGene00003643 I 0.836
NECAME_01500 Necator americanus NECAME_01500 I 0.830
CBN03440 Caenorhabditis brenneri CBN03440 I 0.824
CRE09011 Caenorhabditis remanei CRE09011 I 0.823
PPA29361 Pristionchus pacificus PPA29361 I 0.817
SMUV_0000909301 Syphacia muris SMUV_0000909301 I 0.810
EVEC_0001095701 Enterobius vermicularis EVEC_0001095701 I 0.805
CRE17355 Caenorhabditis remanei CRE17355 I 0.796
CBN18264 Caenorhabditis brenneri CBN18264 I 0.794
CBG04789 Caenorhabditis briggsae CBG04789 I 0.794
BXY_1188800 Bursaphelenchus xylophilus BXY_1188800 N 0.782
ASIM_0000109601 Anisakis simplex ASIM_0000109601 N 0.773
L898_g18539 Steinernema monticolum L898_g18539 I 0.760
TCNE_0001892601 Toxocara canis TCNE_0001892601 N 0.757