nhr-213 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00011520 T306288_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including excretory system; intestine; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-142
M00703_2.00 		Caenorhabditis elegans
RGTCACAR
YTGTGACY		 PBM
Narasimhan et al.(2015)
pTH10714 		0.924 0.629
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.884 0.543
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
T06C12.13a Nuclear receptor 22 94
T06C12.13b Nuclear receptor 22 94

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

77 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE08691 Caenorhabditis remanei CRE08691 I 0.982
nhr-178 Caenorhabditis elegans WBGene00017510 I 0.972
nhr-102 Caenorhabditis elegans WBGene00003692 I 0.970
CBG06601 Caenorhabditis briggsae CBG06601 I 0.968
CRE18430 Caenorhabditis remanei CRE18430 I 0.968
CBG06611 Caenorhabditis briggsae CBG06611 I 0.968
CBG22870 Caenorhabditis briggsae CBG22870 I 0.965
HCOI00483700 Haemonchus contortus HCOI00483700 I 0.960
HPLM_0000277901 Haemonchus placei HPLM_0000277901 I 0.960
ANCCEY_13226 Ancylostoma ceylanicum ANCCEY_13226 I 0.960
NBR_0001218401 Nippostrongylus brasiliensis NBR_0001218401 I 0.955
SVUK_0002058501 Strongylus vulgaris SVUK_0002058501 I 0.944
CBG09320 Caenorhabditis briggsae CBG09320 I 0.943
CRE31070 Caenorhabditis remanei CRE31070 I 0.943
ACOC_0000492601 Angiostrongylus costaricensis ACOC_0000492601 I 0.943
CJA28065 Caenorhabditis japonica CJA28065 I 0.941
CJA09697 Caenorhabditis japonica CJA09697 I 0.933
nhr-142 Caenorhabditis elegans WBGene00018430 D 0.924
CBN28290 Caenorhabditis brenneri CBN28290 I 0.923
CBN21486 Caenorhabditis brenneri CBN21486 I 0.923
SVUK_0001603001 Strongylus vulgaris SVUK_0001603001 I 0.915
CBG09567 Caenorhabditis briggsae CBG09567 I 0.906
scaffold31-EXSNAP2012.20 Pristionchus exspectatus scaffold31-EXSNAP2012.20 I 0.901
CRE30948 Caenorhabditis remanei CRE30948 I 0.891
NBR_0001834701 Nippostrongylus brasiliensis NBR_0001834701 I 0.885
L596_g14586 Steinernema carpocapsae L596_g14586 I 0.885
nhr-232 Caenorhabditis elegans WBGene00012494 D 0.884
CBG20727 Caenorhabditis briggsae CBG20727 I 0.867
nhr-54 Caenorhabditis elegans WBGene00003644 I 0.861
augustus_masked-nMf.1.1.scaf21762-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf21762-processed-gene-0.0 I 0.858
HPLM_0000974401 Haemonchus placei HPLM_0000974401 I 0.856
nhr-231 Caenorhabditis elegans WBGene00012449 I 0.850
Minc14668 Meloidogyne incognita Minc14668 I 0.847
HPBE_0001646201 Heligmosomoides bakeri HPBE_0001646201 I 0.841
MhA1_Contig1192.frz3.gene3 Meloidogyne hapla MhA1_Contig1192.frz3.gene3 I 0.840
CBG20729 Caenorhabditis briggsae CBG20729 I 0.839
CRE15675 Caenorhabditis remanei CRE15675 I 0.838
L898_g3514 Steinernema monticolum L898_g3514 I 0.836
ANCCEY_07914 Ancylostoma ceylanicum ANCCEY_07914 I 0.835
L898_g12798 Steinernema monticolum L898_g12798 I 0.832
nhr-170 Caenorhabditis elegans WBGene00008309 I 0.831
CRE15644 Caenorhabditis remanei CRE15644 I 0.829
L898_g3512 Steinernema monticolum L898_g3512 I 0.829
CBN23838 Caenorhabditis brenneri CBN23838 I 0.829
nhr-45 Caenorhabditis elegans WBGene00003635 I 0.825
HCOI01190000 Haemonchus contortus HCOI01190000 I 0.825
HPLM_0000974301 Haemonchus placei HPLM_0000974301 I 0.825
CRE00301 Caenorhabditis remanei CRE00301 I 0.825
CBN12210 Caenorhabditis brenneri CBN12210 I 0.825
CBG14515 Caenorhabditis briggsae CBG14515 I 0.825
CJA02156 Caenorhabditis japonica CJA02156 I 0.825
L892_g2782 Steinernema scapterisci L892_g2782 I 0.814
L596_g14589 Steinernema carpocapsae L596_g14589 I 0.811
GPLIN_000282900 Globodera pallida GPLIN_000282900 I 0.801
nhr-30 Caenorhabditis elegans WBGene00016091 N 0.800
L892_g2781 Steinernema scapterisci L892_g2781 I 0.788
L596_g14588 Steinernema carpocapsae L596_g14588 I 0.784
SMUV_0000241401 Syphacia muris SMUV_0000241401 I 0.783
L889_g6695 Steinernema feltiae L889_g6695 I 0.782
SMUV_0000241501 Syphacia muris SMUV_0000241501 N 0.777
CBN13200 Caenorhabditis brenneri CBN13200 I 0.777
CBG06599 Caenorhabditis briggsae CBG06599 I 0.776
CBG06609 Caenorhabditis briggsae CBG06609 I 0.776
EVEC_0000956701 Enterobius vermicularis EVEC_0000956701 I 0.775
L889_g6692 Steinernema feltiae L889_g6692 I 0.774
L889_g6696 Steinernema feltiae L889_g6696 I 0.772
CBG19169 Caenorhabditis briggsae CBG19169 I 0.772
CRE15097 Caenorhabditis remanei CRE15097 I 0.771
CRE10693 Caenorhabditis remanei CRE10693 I 0.771
nhr-218 Caenorhabditis elegans WBGene00011750 I 0.767
L898_g19021 Steinernema monticolum L898_g19021 I 0.762
L893_g18997 Steinernema glaseri L893_g18997 I 0.759
L898_g3515 Steinernema monticolum L898_g3515 I 0.758
L596_g14596 Steinernema carpocapsae L596_g14596 I 0.757
NBR_0001834801 Nippostrongylus brasiliensis NBR_0001834801 I 0.747
nhr-130 Caenorhabditis elegans WBGene00003720 I 0.745