ENSP00000259803 (Macaca fascicularis)
GCM

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF03615 (GCM) IPR003902 ENSP00000259803 T198163_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
GCM1
M02020_2.00
Homo sapiens
NVTVNGGGN

NCCCNBABN
PBM
Weirauch et al.(2014)
pTH7965
1.000 1.000
GCM1
M03068_2.00
Homo sapiens
BATGCGGGTR

YACCCGCATV
SELEX
Jolma et al.(2013)
GCM1_1
1.000 1.000
GCM1
M03069_2.00
Homo sapiens
RTRYKGGYRCCMGYAN

NTRCKGGYRCCMRYAY
SELEX
Jolma et al.(2013)
GCM1_2
1.000 1.000
GCM1
M03070_2.00
Homo sapiens
BATGCGGGTRS

SYACCCGCATV
SELEX
Jolma et al.(2013)
GCM1_3
1.000 1.000
GCM1
M04883_2.00
Homo sapiens
RTGSGGGBV

BVCCCSCAY
SELEX
Yin et al.(2017)
GCM1_eDBD_HT-SELEX
1.000 1.000
GCM1
M05868_2.00
Homo sapiens
ATGCGGGYV

BRCCCGCAT
SMiLE-seq
Isakova et al.(2017)
GCM1
1.000 1.000
GCM1
M10603_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$GCMA_Q4
1.000 1.000
GCM1
M10604_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$GCM_Q2
1.000 1.000
GCM1
M04884_2.00
Homo sapiens
ATRNKGGYV

BRCCMNYAT
SELEX
Yin et al.(2017)
GCM1_eDBD_Methyl-HT-SELEX
1.000 1.000
Gcm1
M00168_2.00
Mus musculus
NVTRVGGGY

RCCCBYABN
PBM
Badis et al.(2009)
Gcm1_3732
0.935 0.935
Gcm1
M02022_2.00
Rattus norvegicus
NNRTRVGGGY

RCCCBYAYNN
PBM
Weirauch et al.(2014)
pTH9283
0.928 0.928
XP_004449939.1
M02027_2.00
Dasypus novemcinctus
RTRSGGGY

RCCCSYAY
PBM
Weirauch et al.(2014)
pTH9259
0.913 0.913
GCM1
M02021_2.00
Meleagris gallopavo
VTVNKGGYNN

NNRCCMNBAB
PBM
Weirauch et al.(2014)
pTH8653
0.877 0.877
GCM2
M02023_2.00
Taeniopygia guttata
NRTRHKGGYN

NRCCMDYAYN
PBM
Weirauch et al.(2014)
pTH9341
0.746 0.746
gcm2
M02024_2.00
Tetraodon nigroviridis
ATRCGGGY

RCCCGYAT
PBM
Weirauch et al.(2014)
pTH9386
0.710 0.710
ENSTRUG00000003586
M02025_2.00
Takifugu rubripes
NRTRNGGGYN

NRCCCNYAYN
PBM
Weirauch et al.(2014)
pTH9357
0.703 0.703
GCM2
M03067_2.00
Homo sapiens
NATGCGGGYD

HRCCCGCATN
SELEX
Jolma et al.(2013)
GCM2_1
0.696 0.696
GCM2
M04881_2.00
Homo sapiens
RTGCGGGYN

NRCCCGCAY
SELEX
Yin et al.(2017)
GCM2_FL_HT-SELEX
0.696 0.696
GCM2
M10602_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$GCMB_Q2
0.696 0.696
GCM2
M04882_2.00
Homo sapiens
ATRHKGGYN

NRCCMDYAT
SELEX
Yin et al.(2017)
GCM2_FL_Methyl-HT-SELEX
0.696 0.696
For this family, TFs with SR scores > 0.607 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000259803 GCM 30 167

Links

Other GCM family TFs
Other Macaca fascicularis TFs

146 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
GCM1 Homo sapiens ENSG00000137270 D 1.000
GCM1 Pan troglodytes ENSPTRG00000018288 I 1.000
GCM1 Macaca mulatta ENSMMUG00000022083 I 1.000
GCM1 Callithrix jacchus ENSCJAG00000011189 I 1.000
GCM1 Gorilla gorilla ENSGGOG00000006527 I 1.000
ENSCSAG00000013148 Chlorocebus sabaeus ENSCSAG00000013148 I 1.000
ENSPPYG00000016719 Pongo abelii ENSPPYG00000016719 I 1.000
ENSNLEG00000003544 Nomascus leucogenys ENSNLEG00000003544 I 1.000
GCM1 Felis catus ENSFCAG00000009490 I 0.971
GCM1 Canis familiaris ENSCAFG00000002273 I 0.971
ENSMPUG00000008870 Mustela putorius furo ENSMPUG00000008870 I 0.971
ENSAMEG00000005755 Ailuropoda melanoleuca ENSAMEG00000005755 I 0.964
GCM1 Oryctolagus cuniculus ENSOCUG00000009246 I 0.963
ENSSSCG00000002630 Sus scrofa ENSSSCG00000002630 I 0.957
ENSMICG00000002274 Microcebus murinus ENSMICG00000002274 I 0.949
GCM1 Loxodonta africana ENSLAFG00000012093 I 0.949
GCM1 Otolemur garnettii ENSOGAG00000007879 I 0.942
GCM1 Bos taurus ENSBTAG00000008148 I 0.942
ENSSHAG00000015905 Sarcophilus harrisii ENSSHAG00000015905 I 0.942
ENSBTAP00000010709-D1 Bos grunniens ENSBTAP00000010709-D1 I 0.942
ENSOARG00000015312 Ovis aries ENSOARG00000015312 I 0.942
GCM1 Monodelphis domestica ENSMODG00000018803 I 0.942
GCM1 Equus caballus ENSECAG00000014228 I 0.935
GCM1 Pteropus vampyrus ENSPVAG00000013341 I 0.935
Gcm1 Mus musculus ENSMUSG00000023333 D 0.935
ENSMEUG00000004103 Macropus eugenii ENSMEUG00000004103 I 0.935
GCM1 Erinaceus europaeus ENSEEUG00000013606 I 0.931
Gcm1 Rattus norvegicus ENSRNOG00000007932 D 0.928
GCM1 Tursiops truncatus ENSTTRG00000015250 I 0.928
Myotis_brandtii_Gcm1_10005135 Myotis brandtii Myotis_brandtii_Gcm1_10005135 I 0.920
GCM1 Myotis lucifugus ENSMLUG00000002762 I 0.920
ENSCPOG00000006856 Cavia porcellus ENSCPOG00000006856 I 0.920
GCM1 Vicugna pacos ENSVPAG00000006379 I 0.920
XP_004449939.1 Dasypus novemcinctus XP_004449939.1 D 0.913
GCM1 Dasypus novemcinctus ENSDNOG00000016682 I 0.913
Gcm1 Dipodomys ordii ENSDORG00000003627 I 0.906
ENSSTOG00000022342 Ictidomys tridecemlineatus ENSSTOG00000022342 I 0.899
ENSTSYG00000000507 Tarsius syrichta ENSTSYG00000000507 I 0.899
ENSPSIG00000013518 Pelodiscus sinensis ENSPSIG00000013518 I 0.891
ENSAPLG00000004160 Anas platyrhynchos ENSAPLG00000004160 I 0.877
GCM1 Meleagris gallopavo ENSMGAG00000013927 D 0.877
ENSFALG00000001854 Ficedula albicollis ENSFALG00000001854 I 0.877
Aan_R001196 Calypte anna Aan_R001196 I 0.877
GCM1 Gallus gallus ENSGALG00000016316 I 0.870
ENSSTOG00000014763 Ictidomys tridecemlineatus ENSSTOG00000014763 I 0.868
Gfo_R013721 Geospiza fortis Gfo_R013721 I 0.862
ENSTGUG00000012867 Taeniopygia guttata ENSTGUG00000012867 I 0.862
Afo_R000272 Aptenodytes forsteri Afo_R000272 I 0.855
Brh_R000788 Buceros rhinoceros Brh_R000788 I 0.855
Tal_R009935 Tyto alba Tal_R009935 I 0.848
Pvit_03812 Pogona vitticeps Pvit_03812 I 0.848
gcm1.S Xenopus laevis XB-GENE-6252686 I 0.819
ENSETEG00000005181 Echinops telfairi ENSETEG00000005181 I 0.797
ENSLACG00000003372 Latimeria chalumnae ENSLACG00000003372 I 0.775
GCM1 Ochotona princeps ENSOPRG00000003290 I 0.761
ENSPMAG00000009211 Petromyzon marinus ENSPMAG00000009211 I 0.754
Brh_R007088 Buceros rhinoceros Brh_R007088 I 0.754
GCM2 Taeniopygia guttata ENSTGUG00000005756 D 0.746
Aan_R001550 Calypte anna Aan_R001550 I 0.746
ENSLOCG00000016883 Lepisosteus oculatus ENSLOCG00000016883 I 0.746
Afo_R013226 Aptenodytes forsteri Afo_R013226 I 0.746
ENSAPLG00000002817 Anas platyrhynchos ENSAPLG00000002817 I 0.746
ENSFALG00000013344 Ficedula albicollis ENSFALG00000013344 I 0.746
Gfo_R006501 Geospiza fortis Gfo_R006501 I 0.746
GCM2 Gallus gallus ENSGALG00000012768 I 0.739
GCM2 Meleagris gallopavo ENSMGAG00000003533 I 0.739
Alligator_sinensis_CCG000160.1 Alligator sinensis Alligator_sinensis_CCG000160.1 I 0.739
gcm2 Danio rerio ENSDARG00000045413 I 0.739
Pvit_11235 Pogona vitticeps Pvit_11235 I 0.732
GCM2 Anolis carolinensis ENSACAG00000008677 I 0.732
ENSPSIG00000004698 Pelodiscus sinensis ENSPSIG00000004698 I 0.725
gcm2.S Xenopus laevis XB-GENE-866131 I 0.725
Alligator_sinensis_CCG008975.1 Alligator sinensis Alligator_sinensis_CCG008975.1 I 0.725
ENSAMXG00000006073 Astyanax mexicanus ENSAMXG00000006073 I 0.725
ENSONIG00000009885 Oreochromis niloticus ENSONIG00000009885 I 0.717
ENSACAG00000008561 Anolis carolinensis ENSACAG00000008561 I 0.717
ENSLACG00000009363 Latimeria chalumnae ENSLACG00000009363 I 0.717
gcm2 Xenopus tropicalis XB-GENE-492156 I 0.717
GCM2 Ornithorhynchus anatinus ENSOANG00000007191 I 0.710
ENSMICG00000004238 Microcebus murinus ENSMICG00000004238 I 0.710
gcm2 Tetraodon nigroviridis ENSTNIG00000005042 D 0.710
ENSLOCG00000013145 Lepisosteus oculatus ENSLOCG00000013145 I 0.710
ENSTSYG00000006813 Tarsius syrichta ENSTSYG00000006813 I 0.710
gcm2 Oryzias latipes ENSORLG00000019715 I 0.710
Cmyd_10006831 Chelonia mydas Cmyd_10006831 I 0.710
ENSXMAG00000002726 Xiphophorus maculatus ENSXMAG00000002726 I 0.710
ENSPFOG00000008781 Poecilia formosa ENSPFOG00000008781 I 0.710
GCM2 Bos taurus ENSBTAG00000018787 I 0.703
GCM2 Tursiops truncatus ENSTTRG00000003674 I 0.703
gcm2 Gasterosteus aculeatus ENSGACG00000001157 I 0.703
ENSOARG00000015521 Ovis aries ENSOARG00000015521 I 0.703
ENSPANG00000026314 Papio anubis ENSPANG00000026314 I 0.703
ENSP00000368805-D1 Bos grunniens ENSP00000368805-D1 I 0.703
GCM2 Cavia porcellus ENSCPOG00000011254 I 0.703
ENSTRUG00000003586 Takifugu rubripes ENSTRUG00000003586 D 0.703
GCM2 Tupaia belangeri ENSTBEG00000006181 I 0.696
ENSP00000368805 Macaca fascicularis ENSP00000368805 I 0.696
GCM2 Otolemur garnettii ENSOGAG00000012176 I 0.696
GCM2 Macaca mulatta ENSMMUG00000007719 I 0.696
GCM2 Monodelphis domestica ENSMODG00000010371 I 0.696
ENSMPUG00000000633 Mustela putorius furo ENSMPUG00000000633 I 0.696
ENSNLEG00000000645 Nomascus leucogenys ENSNLEG00000000645 I 0.696
ENSGMOG00000012709 Gadus morhua ENSGMOG00000012709 I 0.696
GCM2 Gorilla gorilla ENSGGOG00000023360 I 0.696
GCM2 Callithrix jacchus ENSCJAG00000019182 I 0.696
ENSCSAG00000007467 Chlorocebus sabaeus ENSCSAG00000007467 I 0.696
GCM2 Felis catus ENSFCAG00000001608 I 0.696
GCM2 Homo sapiens ENSG00000124827 D 0.696
GCM2 Canis familiaris ENSCAFG00000009747 I 0.696
Gcm2 Mus musculus ENSMUSG00000021362 I 0.696
ENSPPYG00000016228 Pongo abelii ENSPPYG00000016228 I 0.696
GCM2 Pan troglodytes ENSPTRG00000017724 I 0.696
GCM2 Oryctolagus cuniculus ENSOCUG00000017698 I 0.696
ENSSHAG00000010590 Sarcophilus harrisii ENSSHAG00000010590 I 0.696
Gcm2 Rattus norvegicus ENSRNOG00000015008 I 0.688
ENSSTOG00000009563 Ictidomys tridecemlineatus ENSSTOG00000009563 I 0.688
GCM2 Equus caballus ENSECAG00000017632 I 0.688
GCM2 Choloepus hoffmanni ENSCHOG00000011562 I 0.688
ENSAMEG00000002669 Ailuropoda melanoleuca ENSAMEG00000002669 I 0.688
GCM2 Ochotona princeps ENSOPRG00000012641 I 0.688
GCM2 Vicugna pacos ENSVPAG00000003006 I 0.688
GCM2 Dasypus novemcinctus ENSDNOG00000003701 I 0.681
GCM2 Myotis lucifugus ENSMLUG00000004637 I 0.674
GCM2 Procavia capensis ENSPCAG00000011887 I 0.667
GCM2 Loxodonta africana ENSLAFG00000007475 I 0.667
GCM2 Pteropus vampyrus ENSPVAG00000004876 I 0.667
GCM2 Echinops telfairi ENSETEG00000012473 I 0.661
Ogr12931 Ophisaurus gracilis Ogr12931 I 0.645
CGI_10019940 Crassostrea gigas CGI_10019940 I 0.630
Sakowv30018670m.g Saccoglossus kowalevskii Sakowv30018670m.g I 0.623
AFUN009837 Anopheles funestus AFUN009837 I 0.623
AAEL000623 Aedes aegypti AAEL000623 I 0.623
AMIN006368 Anopheles minimus AMIN006368 I 0.616
AQUA003642 Anopheles quadriannulatus AQUA003642 I 0.616
AGAP007783 Anopheles gambiae AGAP007783 I 0.616
AMAM003661 Anopheles maculatus AMAM003661 I 0.616
ASTEI01672 Anopheles stephensi ASTEI01672 I 0.616
AMAM005757 Anopheles maculatus AMAM005757 I 0.615
tetur09g06060 Tetranychus urticae tetur09g06060 I 0.614
AMEM005966 Anopheles merus AMEM005966 I 0.609
ACOM031025 Anopheles coluzzii ACOM031025 I 0.609
CapteG133139 Capitella teleta CapteG133139 I 0.609
AALB008013 Anopheles albimanus AALB008013 I 0.609
AARA011980 Anopheles arabiensis AARA011980 I 0.609
ADIR000711 Anopheles dirus ADIR000711 I 0.609
AFAF005680 Anopheles farauti AFAF005680 I 0.609